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Books : Health, Mind & Body : Disorders & Diseases : Epilepsy
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Causes,Symptoms,and Treatments for this disorder.
There are many possible causes of epilepsy,but in 70% of the cases there is no known cause. Most people are not born with epilepsy. This disorder can strike anyone,primarily children and young adults.
Because at times seizures involves loss of some body control or completely all control, epileptic seizures are dangerous,and they can be embarrassing.
Here are some ways to lesson the seizures associated with Epilepsy. -
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Drug resistance in epilepsy is an important clinical problem. About 200f patients diagnosed as having epilepsy fail to respond to prescribed antiepileptic drugs and continue to have seizures. But despite the size of the problem, remarkably little attention has been paid to the biological basis of refractory epilepsy. Recent work has shown that brain tissue from some patients with epilepsy shows increased expression of a protein that mediates drug resistance in cancer, P glycoprotein. But while resistance in cancer has been extensively studied, and trials of reversal of resistance have been undertaken with some success, resistance in epilepsy has only just begun to be addressed. This novel book brings together, for the first time, epilepsy researchers and oncologists, with a view to stimulating further work on drug resistance in epilepsy. Successfully bridging the two fields, the stimulating discussions contained in this book should be of great interest to those working on cancer resistance and refractory epilepsy alike.
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Intractable Focal Epilepsy is a definitive multi-author reference work covering the most difficult to treat epilepsies. The natural history, pathology and Treatment, both medical and surgical, of the conditions underlying intractable seizures are fully described and illustrated. Including contributions from North America, Europe and the Pacific Rim, the emphasis throughout is on clinical diagnosis and treatment - both medical and surgical, and their respective outcomes. The text is enhanced by over 250 illustrations, and the clear modern design enables the reader to assimilate information quickly.
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Epilepsy has afflicted humankind throughout recorded history; yet, it is only in the last half-century, that significant progress has been made in our basic understanding of the epileptic brain. Pivotal advances in drug development and surgical techniques, as well as the emergence of innovative approaches such as electrical stimulation of the nervous system, have led to a substantial reduction in the morbidity and mortality of patients with epilepsy. At the same time, remarkable developments in neuroscience have enhanced our understanding of brain structure and function.
Epilepsy: Mechanisms, Models, and Translational Perspectives incorporates new translational advances that bring epilepsy therapies from the laboratory bench to the bedside and back again. It brings together the work of more than 70 of the field’s most respected and cutting-edge researchers and clinicians. In 24 chapters, this extraordinarily comprehensive and current work—
- Offers an overview of the basic anatomic and functional substrates of seizure genesis and considers novel pathogenic concepts that have both emerged and been validated experimentally
- Examines antiepileptic drug therapy, including the latest on molecular targets
- Looks at the state of surgical treatments for epilepsy and discusses advances in the fields of structural and functional neuroimaging
- Reviews the variety of nontraditional therapeutic options, such as the ketogenic diet, the vagus nerve stimulator, immunomodulators, neurosteroids, herbs, and botanicals
- Investigates neuroendocrine, hormonal, and biobehavioral factors that influence seizure susceptibility—information that can be incorporated into the design of treatment algorithms on an individualized basis
- Provides a glimpse of what future epilepsy therapies might look like, from novel mechanisms of drug delivery to gene and stem-cell therapies for epilepsy to seizure detection methods, to the ultimate goal of disease prevention.
The idea for this book was inspired by the editors’ collective desire to promote bridging of the so-called translational divide—that is, covering innovative treatment strategies based on scientific principles that have yet to be tested rigorously in the clinical setting, but yet may provide practitioners with new and promising approaches toward epilepsy therapeutics.
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About 20% of people with epilepsy have seizures which are resistant to anticonvulsant medications. These drug-resistant seizures are called `intractable,' and the patients who have them -- about 1 in 500 of the general population -- present a major challenge to neurologists and epilepsy associations. The present volume describes the symptomatology of the major `intractable' syndromes, the most appropriate drugs for each, and the possibilities for surgical control. Research related to the causes and effects of unchecked seizures is presented, and new directions in prevention and therapy are discussed.
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In March 2001, the National Institutes of Health issued the following warning: "The number of Web sites offering health-related resources grows every day. Many sites provide valuable information, while others may have information that is unreliable or misleading." Furthermore, because of the rapid increase in Internet-based information, many hours can be wasted searching, selecting, and printing.This book was created for medical professionals, students, and members of the general public who want to conduct medical research using the most advanced tools available and spending the least amount of time doing so.
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Evaluation of neuronal responses to single-pulse electrical stimulation (SPES) was performed to determine the reliability of cortical stimulation under general anaesthesia compared to alert awareness. Nine patients with intractable epilepsy, candidates for epilepsy surgery, underwent SPES during both electrode implantation and telemetry recording. Early, delayed, repeated, fixed and oscillatory neuronal responses to SPES were investigated. Analysis showed that: a) early responses are normal markers of synaptic efficacy, b) delayed responses are markers of epileptogenicity, c) repeated responses are normal variants of deep cortical stimulation, d) fixed responses are markers of normal connectivity underlying sensory processing functions, and e) oscillatory responses are normal markers of pacemaking capability of deep brain structures. This study produced evidence that the main pathological markers have a high correlation between implantation and telemetry SPES procedures. Results render SPES an equally reliable process under both anaesthesia and alert awareness.
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Over the past 20 years, a silent revolution in functional neurosurgery has been unfolding. This revolution, still in the making, is the development of cortical electrical neuromodulation. No book covering the field of therapeutic cortical stimulation exists and only scarce attention has been given to this new field of neuromodulation in all textbooks and related books. As a result, the majority of neurologists and neurosurgeons are unaware of this technology. The aim of this book is thus twofold: cross-fertilisation among neurologists, other health professionals and functional neurosurgeons, and defining indications and limits of cortical stimulation, invasive and non-invasive. This textbook brings together leading authorities from all over the world and provides for the first time a complete account of the field. As a 'teaching' tool, all, beginners and non, will find a conclusive word in a rapidly evolving field.
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At his Manhattan North Hospital Office, Steve Coughlin's job is complicated by an invisible companion - epilepsy. Its seizures have defied every effort to control them and force him to take them into account with everything he does.
When he becomes a patient of the hospital's best neurologist, Dr. Diane Schneider, he hopes she's the one who can stop them. They've nearly killed him more than once and he knows his luck won't hold out forever. But she recommends unexpected hospitalizations and medicine changes that turn his life upside-down.
His already-suspicious wife thinks he's cheating on her and leaves him. He's demoted at work. Schneider illegally gives his case to the hospital's human resources department, which insists that he "voluntarily" commit himself to their psychiatric hospital or look for a new job. Not seeing a way around their threat, he complies. After he's discharged, he's fired anyway.
Jobless and alone, he confides in his close friend, Melissa. In time they grow closer. They want to put the hospital experience behind them, but don't understand why Steve wasn't fired like other people - why the hopsital insisted upon making him a psychiatric patient first. Hallucinations, suicides, cyber-stalkers and other nightmares will make them fear for their sanity and lives before they find the surprising answer. -
This fascinating book presents accounts of seizures and epilepsy written by adult patients in their own words. These personal, heartfelt passages realistically detail the feelings experienced before, during, and after a wide variety of seizures. The book also contains statements by some of these patients about what life with epilepsy is like, including the fear of having a seizure, the social and occupational problems encountered, and the psychological impact of the stigma still prevalent in our culture.
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Get The Facts About Epilepsy So You Can Take Back Control Of Your Life
Discover How To Recapture Your Quality Of Life After A Diagnosis Of Epilepsy
Are you ready to take charge of your life? Discover important facts about epilepsy including tips on living with epilepsy and epilepsy diagnosis and treatment information.
Do you or someone you know suffer from epilepsy? A diagnosis of epilepsy can be frightening, but with the right information and knowledge, you can go on to live a high quality life and control epilepsy using several important tips and insights.
Each year over 3 million Americans suffer from epilepsy and seizures associated with epilepsy.
According to the CDC and NIH, Doctors Will Diagnose More Than 200,000 New Cases Of Epilepsy Each Year…
Epilepsy is a serious medical condition that affects roughly ten percent of the people living in America. Roughly 3 percent of all people will go on to develop epilepsy during the course of their lifetime.
Do you know if you are at risk for epilepsy?
Peer-reviewed studies suggest that record numbers of epilepsy cases are diagnosed each year at alarming rates. The incidence and prevalence of epilepsy and seizures associated with epilepsy are climbing.
What can you do about it?
Protect yourself from unexpected epilepsy seizures by learning as much as you can about this disease and your treatment choices.
Here are some important facts about epilepsy that you should know:
* Almost 300,000 people will experience their very first epileptic convulsion or seizure each year…
* Of these people, roughly 120,000 epilepsy seizures occur in children younger than 18 years old.
* Children under the age of 5 are just as at risk for seizures associated with febrile convulsions or epilepsy as adults are, yet many parents do not realize this or know what to do if their child experiences a seizure…
* Epilepsy targets people between the ages of 2 and 65+… so virtually no age group is safe from this devastating condition…
Do You Know If You Are At Risk For Epilepsy?
People most at risk for epilepsy include:
* Stroke patients, who are 20 percent more likely to develop epilepsy with time…
* Minority populations, as epilepsy is a condition more likely to affect minorities than non-minority populations…
* People treated with various medications including some anti-depressant or anti-anxiety medications, which doctors commonly prescribe without warning patients of the dangers of serious side effects including convulsions and seizures…
* Are you at risk?
Find Out Now. Even if you don’t fall into one of these categories, you are at risk for epilepsy. For example, roughly 33 percent of all people will have a single epileptic seizure with no identifiable cause during the course of their lifetime. That means billions of people may experience a convulsion at some point in their lives.
Epileptic seizures and convulsions can be frightening if you don’t know what is happening or lack support to help you through difficult times.
Contrary to popular thought, most people with epilepsy can live a good quality of life…
Just because you have epilepsy doesn’t mean you don’t have a good chance for survival. In fact, up to 70 percent of people with epilepsy can enter remission with proper treatment and early diagnosis of their condition.
These same people go on to live a high quality life, and you can too.
Some studies suggest up to 75 percent of people that use seizure medications for up to 5 years can withdraw from their medication and remain symptom free.
You can spend a lifetime trying to sort fact from fiction about epilepsy, or you can take advantage of all the hard work and effort I’ve put into creating a unique guide that will teach you everything you need to know about epilepsy and related convulsions or seizures.
After much time and effort, I’ve created a simple guide that will help you learn everything you need to know to combat epilepsy… -
Though clinical aspects of epilepsy such as seizure control are crucially important to its management, increasing attention is being given to wider quality of life issues. Epilepsy continues to be an often misunderstood and stigmatising condition; for the vast majority of people whose seizures can be well controlled, the social and psychological repercussions are often of greater significance than the seizures themselves.
The increasing emphasis on the importance of non-clinical outcomes in the assessment of new treatments and management strategies for chronic conditions such as epilepsy has stimulated interest in methodological issues in assessing quality of life. This book reviews the recent literature on the impact of epilepsy on everyday experience and the methodological issues involved in assessing that impact. It also considers the perspectives of a range of health professionals involved in caring for people with epilepsy and how, through appropriate management, the impact on their lives ca -
During an epileptic seizure while visiting her ancestral home, sixteen-year-old Katie is transported back in time and mistaken for her great-great-great grandmother who also had epilepsy at a time when the disease was greatly misunderstood.
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Abstract: In this first of two articles on new epilepsy guidelines for primary care physicians, the authors present detailed algorithms for the diagnosis and classification of seizure disorders in adults. They discuss the differentiation between generalized and partial seizures and stress that accurate identification is especially important because the type of seizure determines the appropriate treatment. The second article looks at the treatment portion of the new guidelines.
Patients presenting with a chief report of a possible seizure (ie, a recent paroxysmal neurologic event of sudden onset and brief duration with eventual return to baseline functioning) may pose a quandary for the primary care physician, especially if the event was not witnessed. To determine whether the event was indeed a seizure, the physician should obtain and document a detailed history from the patient (and witnesses) and then search for supportive findings from physical and neurologic examinations, appropriate laboratory tests, and imaging studies.
Although controversial, it is our opinion that all patients being evaluated for a possible seizure disorder should receive a magnetic resonance imaging (MRI) study as part of their evaluation, especially in cases of partial seizures, where identification of focal brain lesions is crucial (1,2). If an emergency neuroimaging study is indicated and an MRI is not available, computed tomography (CT) of the head without contrast is generally satisfactory to address an urgent need (eg, to rule out cerebral hemorrhage). -
This volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed.
A coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation. -
Living With Epilepsy Have you or a loved one been recently diagnosed with epilepsy? If so, your immediate goal is to become seizure-free. Working closely with your physician to begin treatment is the top priority. However, you can’t have enough information about how to live with this disorder and Living With Epilepsy is written to give you answers to some of the basic questions about epilepsy and its treatments. For instance did you know that seizures are the only visible symptom of epilepsy? Did you know that there are different types of seizures and that not everyone displays the same symptoms in the same way? Finally, did you know that there are other types of seizures that do not necessarily diagnose as epilepsy but are in fact a result of some other disorder? You need answers to these and the multitude of other questions if you are to be armed with the right ammunition when suspecting epilepsy in yourself or a loved one. Epilepsy is the considered the second most common disease in America and is prevalent in over one percent of Americans each year. 125,000 to 150,000 people are diagnosed each year. 30 percent of those diagnosed are children. Early diagnosis is crucial to avoid dangerous or life-threatening situations to yourself or others. There is no cure for epilepsy but there are anti-seizure medications that can reduce and in some cases prevent the incidence of seizures. Living With Epilepsy is an excellent handbook to learn the history of epilepsy, study the different types of seizures and examine some of the available treatments. Knowledge is power and Living With Epilepsy can help you to understand what kinds of questions you should be asking your health care provider. Take a look at what’s inside: The History of Epilepsy What Is Epilepsy? What Are Seizures? Who Is At Risk For Epilepsy? What Are the Causes? Is Epilepsy Genetic? Is Epilepsy Congenital - Will I have it forever? What Is SUDEP (sudden, unexpected death of someone with epilepsy) What Are the Different Types of Epilepsy and Seizures? How Does Epilepsy Affect Thinking and Memory? Epilepsy and Moods, Behavior and Sleep How Is Epilepsy Diagnosed? What Treatments Are Available for Epilepsy? Epilepsy and Diet and Nutrition Living With Epilepsy Living With Epilepsy is no replacement for medical advice and should not be construed as such. Rather, it is a valuable tool to arm yourself with important information regarding the diagnosis and treatment of this disorder. Remember, epilepsy is not a mental illness nor is it contagious. It is also not a result of low intelligence. From seizure to seizure someone with epilepsy is no different that anyone and is perfectly normal. Again, if you or a loved one suspects they have epilepsy or are diagnosed with epilepsy you need answers. Living With Epilepsy is just what you need to become informed. Order your copy now and have your answers in minutes!
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